Cefetamet
Chemical compound
- J01DD10 (WHO)
- (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-
2-methoxyiminoacetyl]amino}-3-methyl-8-oxo-
5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- 65052-63-3
- 5487888
- 4589562
- 4R5TV783X3
- D03424
- (Nice) (Nice)2 ChEMBL55869 (Nice) (Nice)2
- DTXSID00867110
- Interactive image
- O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)C(=N\OC)/c3nc(sc3)N)C)C(=O)O
InChI
- InChI=1S/C14H15N5O5S2/c1-5-3-25-12-8(11(21)19(12)9(5)13(22)23)17-10(20)7(18-24-2)6-4-26-14(15)16-6/h4,8,12H,3H2,1-2H3,(H2,15,16)(H,17,20)(H,22,23)/b18-7-/t8-,12-/m1/s1
- Key:MQLRYUCJDNBWMV-GHXIOONMSA-N
Cefetamet is a cephalosporin antibiotic.[1][2]
References
- ^ Pubchem. "Cefetamet". pubchem.ncbi.nlm.nih.gov. Retrieved 2018-03-23.
- ^ Bryson HM, Brogden RN (April 1993). "Cefetamet pivoxil. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use". Drugs. 45 (4): 589–621. doi:10.2165/00003495-199345040-00009. PMID 7684677. S2CID 264011171.
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(inhibit synthesis
of peptidoglycan
layer of bacterial
cell wall by binding
to and inhibiting
PBPs, a group of
D-alanyl-D-alanine
transpeptidases)
Glycopeptides Lipoglycopeptides |
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Lipopeptides |
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Polymyxins |
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Other |
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- Inhibit PG subunit synthesis and transport: NAM synthesis inhibition (Fosfomycin)
- DADAL/AR inhibitors (Cycloserine)
- bactoprenol inhibitors (Bacitracin)
- Hydrolyze NAM-NAG
- Tyrothricin
- Isoniazid#
- Teixobactin
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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