Isoaminile
Chemical compound
- R05DB04 (WHO)
- 4-(dimethylamino)-2-isopropyl-2-phenylpentanenitrile
- 77-51-0 Y
- 6481
- DB08944 N
- 6236 Y
- R4823W2PQL
- D08088 Y
- DTXSID5057830
- Interactive image
- N#CC(c1ccccc1)(C(C)C)CC(N(C)C)C
InChI
- InChI=1S/C16H24N2/c1-13(2)16(12-17,11-14(3)18(4)5)15-9-7-6-8-10-15/h6-10,13-14H,11H2,1-5H3 Y
- Key:WFLSCFISQHLEED-UHFFFAOYSA-N Y
Isoaminile is an antitussive (cough suppressant) used under the trade-name Peracon.[1]
The normal therapeutic dose is 40–80 mg of the cyclamate salt, with a maximum of five doses in a 24-hour period.[citation needed] In addition to its central antitussive effects, it is also an anticholinergic, exhibiting both antimuscarinic and antinicotinic actions.[citation needed]
References
- ^ Chappel CI, von Seeman C (1963). "Antitussive Drugs". In Ellis GP, West GB (eds.). Progress in Medicinal Chemistry. Vol. 3. Butterworth. pp. 114–115. doi:10.1016/S0079-6468(08)70117-6. ISBN 978-0-444-53322-7. PMID 14146305. Retrieved 2013-09-12.
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Cough and cold preparations (R05)
- Acetylcysteine#
- Ambroxol
- Bromhexine
- Carbocisteine
- Dembrexine hydrochloride
- Domiodol
- Dornase alfa
- Eprazinone
- Erdosteine
- Letosteine
- Mannitol
- Mesna
- Neltenexine
- Sobrerol
- Stepronin
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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