Isopropyl myristate

Isopropyl myristate[1]
Isopropyl myristate
Names
Preferred IUPAC name
Propan-2-yl tetradecanoate
Other names
Tetradecanoic acid, 1-methylethyl ester
Myristic acid isopropyl ester
Identifiers
CAS Number
  • 110-27-0 checkY
3D model (JSmol)
  • Interactive image
ChEMBL
  • ChEMBL207602
ChemSpider
  • 7751 checkY
ECHA InfoCard 100.003.412 Edit this at Wikidata
EC Number
  • 203-751-4
KEGG
  • D02296 checkY
MeSH C008205
PubChem CID
  • 8042
RTECS number
  • XB8600000
UNII
  • 0RE8K4LNJS checkY
CompTox Dashboard (EPA)
  • DTXSID0026838 Edit this at Wikidata
InChI
  • InChI=1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3 ☒N
    Key: AXISYYRBXTVTFY-UHFFFAOYSA-N ☒N
  • InChI=1/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3
    Key: AXISYYRBXTVTFY-UHFFFAOYAN
  • CCCCCCCCCCCCCC(=O)OC(C)C
Properties
Chemical formula
 C17H34O2
Molar mass 270.457 g·mol−1
Density 0.85 g/cm3
Boiling point 167 °C (333 °F; 440 K) at 9 mmHg
Hazards
NFPA 704 (fire diamond)
NFPA 704 four-colored diamondHealth 0: Exposure under fire conditions would offer no hazard beyond that of ordinary combustible material. E.g. sodium chlorideFlammability 1: Must be pre-heated before ignition can occur. Flash point over 93 °C (200 °F). E.g. canola oilInstability 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g. liquid nitrogenSpecial hazards (white): no code
0
1
0
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Infobox references
Chemical compound

Isopropyl myristate (IPM) is the ester of isopropyl alcohol and myristic acid.

Uses

Isopropyl myristate is a polar emollient and is used in cosmetic and topical pharmaceutical preparations where skin absorption is desired. It is also used as a treatment for head lice.[2] It is also in flea and tick killing products for pets.

It is used to remove bacteria from the oral cavity as the non-aqueous component of the two-phase mouthwash product "Dentyl pH".

Isopropyl myristate is also used as a solvent in perfume materials, and in the removal process of prosthetic make-up.

Hydrolysis of the ester from isopropyl myristate can liberate the acid and the alcohol. The acid is theorized to be responsible for decreasing of the pH value of formulations.[3][4]

References

  1. ^ "SAFETY DATA SHEET". Fisher Scientific. 2009-09-22. Retrieved 2024-05-05.
  2. ^ "Anti-Lice Treatments". www.lice.ca. Retrieved 2024-05-05.
  3. ^ Wen, Z.; Fang, L. and He, Z. (2009). Effect of chemical enhancers on percutaneous absorption of daphnetin in isopropyl myristate vehicle across rat skin in vitro. Drug Deliv, 16: 214-223
  4. ^ Engelbrecht, T.; Demé, B.; Dobner, B. and Neubert, R. (2012). Study of the influence of the penetration enhancer isopropyl myristate on the nanostructure of stratum corneum lipid model membranes using neutron diffraction and deuterium labelling. Skin Pharmacol Physiol, 25:200-7

External links

  • v
  • t
  • e
FaceLipsEyesHairNailsBodyRelated
Major cosmetic brands
Categories
Companies
People
History