L-165041

Chemical compound
  • N/A
Legal statusLegal status
  • Investigational
Identifiers
  • [4-[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy]acetic acid[1]
CAS Number
  • 79558-09-1
PubChem CID
  • 6603901
IUPHAR/BPS
  • 2691
DrugBank
  • DB08078
ChemSpider
  • 5036209
UNII
  • 7RV682Z3FQ
CompTox Dashboard (EPA)
  • DTXSID6040745 Edit this at Wikidata
Chemical and physical dataFormulaC22H26O7Molar mass402.443 g·mol−13D model (JSmol)
  • Interactive image
  • CCCc1c(ccc(c1O)C(=O)C)OCCCOc2ccc(cc2)OCC(=O)O
InChI
  • InChI=1S/C22H26O7/c1-3-5-19-20(11-10-18(15(2)23)22(19)26)28-13-4-12-27-16-6-8-17(9-7-16)29-14-21(24)25/h6-11,26H,3-5,12-14H2,1-2H3,(H,24,25)
  • Key:HBBVCKCCQCQCTJ-UHFFFAOYSA-N

L-165041 is a phenyloxyacetate PPARδ receptor agonist. It is less potent and PPARδ selective than GW 501516.[2]

See also

References

  1. ^ Iwashita A, Muramatsu Y, Yamazaki T, Muramoto M, Kita Y, Yamazaki S, et al. (March 2007). "Neuroprotective efficacy of the peroxisome proliferator-activated receptor delta-selective agonists in vitro and in vivo". The Journal of Pharmacology and Experimental Therapeutics. 320 (3): 1087–96. doi:10.1124/jpet.106.115758. PMID 17167170. S2CID 9595370.
  2. ^ Atta-ur-Rahman, Reitz AB (2005). Frontiers in Medicinal Chemistry, Volume 2. Bentham Science Publishers. pp. 244–. ISBN 978-1-608-05205-9. Retrieved 2 April 2013.
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