Mucin 6

Protein-coding gene in the species Homo sapiens
MUC6
Identifiers
AliasesMUC6, MUC-6, mucin 6, oligomeric mucus/gel-forming
External IDsOMIM: 158374; MGI: 2663233; HomoloGene: 18768; GeneCards: MUC6; OMA:MUC6 - orthologs
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for MUC6
Genomic location for MUC6
Band11p15.5Start1,012,823 bp[1]
End1,036,718 bp[1]
Gene location (Mouse)
Chromosome 7 (mouse)
Chr.Chromosome 7 (mouse)[2]
Chromosome 7 (mouse)
Genomic location for MUC6
Genomic location for MUC6
Band7 F5|7 87.03 cMStart141,633,456 bp[2]
End141,655,319 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • body of pancreas

  • duodenum

  • body of stomach

  • gallbladder

  • fundus

  • sural nerve

  • islet of Langerhans

  • right lobe of liver

  • right uterine tube

  • canal of the cervix
Top expressed in
  • duodenum

  • stomach

  • neural layer of retina

  • cerebellum

  • tail of embryo

  • skeletal muscle tissue

  • cerebellar cortex

  • human kidney

  • bone marrow

  • granulocyte
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • extracellular matrix structural constituent
Cellular component
  • Golgi lumen
  • extracellular region
  • plasma membrane
Biological process
  • maintenance of gastrointestinal epithelium
  • O-glycan processing
  • stimulatory C-type lectin receptor signaling pathway
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

4588

353328

Ensembl

ENSG00000283350
ENSG00000277281
ENSG00000184956
ENSG00000277518

ENSMUSG00000048191

UniProt

Q6W4X9

Q80T03
Q0VAV1

RefSeq (mRNA)

NM_005961

NM_181729
NM_001330001
NM_001368953

RefSeq (protein)

NP_005952

NP_859418.1
NP_001316930
NP_001355882

Location (UCSC)Chr 11: 1.01 – 1.04 MbChr 7: 141.63 – 141.66 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Mucin 6, oligomeric mucus/gel-forming, also known as MUC6, is a human gene encoding a protein of the same name.[5] MUC6, along with MUC2, MUC5AC, and MUC5B, is located within the 11p15 chromosomal locus of chromosome 11. MUC6, along with MUC1, is expressed in normal pancreases.[6]

References

  1. ^ a b c ENSG00000277281, ENSG00000184956, ENSG00000277518 GRCh38: Ensembl release 89: ENSG00000283350, ENSG00000277281, ENSG00000184956, ENSG00000277518 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000048191 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: MUC6 mucin 6, oligomeric mucus/gel-forming".
  6. ^ Monges GM, Mathoulin-Portier MP (2005). "Role of Mucins in Pancreatic Carcinoma". Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas. 3: 351–356. doi:10.1016/S1874-5784(05)80040-6. ISBN 978-0-12-088404-9.
  • v
  • t
  • e
Mucoproteins
Mucin
Other
Proteoglycans
CS/DS
HS/CS
CS
KS
HS
Other
Stub icon

This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by expanding it.

  • v
  • t
  • e