PSAPL1

Protein-coding gene in the species Homo sapiens
PSAPL1
Identifiers
AliasesPSAPL1, prosaposin-like 1 (gene/pseudogene), prosaposin like 1 (gene/pseudogene), prosaposin like 1
External IDsMGI: 1924193; HomoloGene: 105928; GeneCards: PSAPL1; OMA:PSAPL1 - orthologs
Gene location (Human)
Chromosome 4 (human)
Chr.Chromosome 4 (human)[1]
Chromosome 4 (human)
Genomic location for PSAPL1
Genomic location for PSAPL1
Band4p16.1Start7,430,285 bp[1]
End7,434,930 bp[1]
Gene location (Mouse)
Chromosome 5 (mouse)
Chr.Chromosome 5 (mouse)[2]
Chromosome 5 (mouse)
Genomic location for PSAPL1
Genomic location for PSAPL1
Band5|5 B3Start36,361,365 bp[2]
End36,363,912 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • skin of thigh

  • skin of abdomen

  • vulva

  • nipple

  • skin of hip

  • human penis

  • lower lobe of lung

  • body of stomach

  • pharynx

  • right testis
Top expressed in
  • skin of external ear

  • pyloric antrum

  • epithelium of stomach

  • lip

  • skin of back

  • esophagus

  • conjunctival fornix

  • superior surface of tongue

  • condyle

  • mucous cell of stomach
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • enzyme activator activity
  • G protein-coupled receptor binding
Cellular component
  • extracellular region
  • lysosome
  • extracellular space
  • cytoplasm
  • cytosol
Biological process
  • regulation of lipid metabolic process
  • prostate gland growth
  • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
  • epithelial cell differentiation involved in prostate gland development
  • sphingolipid metabolic process
  • lipid metabolism
  • positive regulation of catalytic activity
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

768239

76943

Ensembl

ENSG00000178597

ENSMUSG00000043430

UniProt

Q6NUJ1

Q8C1C1

RefSeq (mRNA)

NM_001085382

NM_175249

RefSeq (protein)

NP_001078851

NP_780458

Location (UCSC)Chr 4: 7.43 – 7.43 MbChr 5: 36.36 – 36.36 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Proactivator polypeptide-like 1 is a protein in humans that is encoded by the PSAPL1 gene. It is a member of the saposin family of proteins. [5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000178597 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000043430 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Prosaposin-like 1 (gene/pseudogene)". Retrieved 2013-04-11.

Further reading


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