Zolimidine

Zolimidine
Skeletal formula of zolimidine
Ball-and-stick model of the zolimidine molecule
Names
Preferred IUPAC name
2-[4-(Methanesulfonyl)phenyl]imidazo[1,2-a]pyridine
Identifiers
CAS Number
  • 1222-57-7 checkY
3D model (JSmol)
  • Interactive image
ChemSpider
  • 13985 ☒N
ECHA InfoCard 100.013.589 Edit this at Wikidata
KEGG
  • D07075 checkY
PubChem CID
  • 14652
UNII
  • YCF001N8QB checkY
CompTox Dashboard (EPA)
  • DTXSID9057630 Edit this at Wikidata
InChI
  • InChI=1S/C14H12N2O2S/c1-19(17,18)12-7-5-11(6-8-12)13-10-16-9-3-2-4-14(16)15-13/h2-10H,1H3 ☒N
    Key: VSLIUWLPFRVCDL-UHFFFAOYSA-N ☒N
  • InChI=1/C14H12N2O2S/c1-19(17,18)12-7-5-11(6-8-12)13-10-16-9-3-2-4-14(16)15-13/h2-10H,1H3
    Key: VSLIUWLPFRVCDL-UHFFFAOYAK
  • CS(=O)(=O)C1=CC=C(C=C1)C2=CN3C=CC=CC3=N2
Properties
Chemical formula
C14H12N2O2S
Molar mass 272.32 g/mol
Density 1.31 g/cm3
Pharmacology
A02BX10 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Infobox references
Chemical compound

Zolimidine (zoliridine, brand name Solimidin) is a gastroprotective[1] drug previously used for peptic ulcer[2] and gastroesophageal reflux disease.[3]

See also

  • Imidazopyridine

References

  1. ^ Parisio, C; Clementi, F (November 1976). "Surface Alterations Induced by Stress in Gastric Mucosa: Protective Effect of Zolimidine. A Transmission and Scanning Electron Microscope Investigation". Laboratory Investigation. 35 (5): 484–95. PMID 136548.
  2. ^ Belohlavek, D; Malfertheiner, P (1979). "The Effect of Zolimidine, Imidazopyridine-derivate, on the Duodenal Ulcer Healing". Scandinavian Journal of Gastroenterology. Supplement. 54: 44. PMID 161649.
  3. ^ Materia, A; Basso, N; Bagarani, M; Basoli, A; Speranza, V (30 April 1981). "Treatment of Alkaline Reflux Gastritis with Zolimidine. Controlled Study". La Clinica Terapeutica. 97 (2): 183–91. PMID 6453678.
  • v
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Drugs for peptic ulcer and GERD/GORD (A02B)
H2 antagonists ("-tidine")Prostaglandins (E)/
analogues ("-prost-")Proton-pump inhibitors
("-prazole")Potassium-competitive
acid blockers ("-prazan")OthersCombinations
  • See also: Helicobacter pylori eradication protocols


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