B10细胞

B10细胞(英語:B10 cells)是B细胞中调节B细胞(Breg cell)的一个亚群,在人类小鼠中都起抑制免疫响应的作用[1][2][3]。B10细胞因其能分泌抑制性的白细胞介素白细胞介素-10(IL-10)而得名[4][5]

参考文献

  1. ^ Tedder, TF. B10 cells: a functionally defined regulatory B cell subset.. Journal of immunology (Baltimore, Md. : 1950). 15 February 2015, 194 (4): 1395–401. PMID 25663677. doi:10.4049/jimmunol.1401329. 
  2. ^ Candando, KM; Lykken, JM; Tedder, TF. B10 cell regulation of health and disease.. Immunological reviews. May 2014, 259 (1): 259–72. PMID 24712471. doi:10.1111/imr.12176. 
  3. ^ Lykken, JM; Candando, KM; Tedder, TF. Regulatory B10 cell development and function.. International immunology. October 2015, 27 (10): 471–7. PMID 26254185. doi:10.1093/intimm/dxv046. 
  4. ^ Mao, Y; Wang, Y; Dong, L; Zhang, Q; Wang, C; Zhang, Y; Li, X; Fu, Z. Circulating exosomes from esophageal squamous cell carcinoma mediate the generation of B10 and PD-1high Breg cells.. Cancer science. September 2019, 110 (9): 2700–2710. PMID 31276257. doi:10.1111/cas.14122. 
  5. ^ Liu, J; Chen, X; Hao, S; Zhao, H; Pang, L; Wang, L; Ren, H; Wang, C; Mao, H. Human chorionic gonadotropin and IL-35 contribute to the maintenance of peripheral immune tolerance during pregnancy through mediating the generation of IL-10+ or IL-35+ Breg cells.. Experimental cell research. 15 October 2019, 383 (2): 111513. PMID 31362000. doi:10.1016/j.yexcr.2019.111513. 
淋巴细胞/
造血幹細胞淋巴母細胞英语Lymphoblast
  • αβ
    • 细胞毒性CD8+
    • 辅助性CD4+/TFH英语Follicular B helper T cells/Th3英语T helper 3 cell/Th17英语T helper 17 cell/调节T细胞
  • γδT细胞英语Gamma delta T cell
  • 自然T細胞英语Naive T cell
  • 自然杀伤T细胞
淋巴细胞生成英语Lymphopoiesis
描述
  • 生理
    • 細胞
    • 自體抗原
    • 自體抗體
    • 補體
    • 表面抗原
    • 免疫受體英语Template:Immunoglobulin superfamily immune receptors
疾病
  • 過敏英语Template:Allergic conditions
  • 缺陷
  • 失調
  • 過敏和自體免疫疾病
  • 腫瘤
治療
  • 程序
  • 藥物
    • 抗組織胺藥
    • 免疫增强剂
    • 免疫抑制剂
    • 單株抗體英语Template:Monoclonals for immune system