Buphenine

Medication
  • C04AA02 (WHO) G02CA02 (WHO)
Identifiers
  • 4-{1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]propyl}phenol
CAS Number
  • 447-41-6
PubChem CID
  • 4567
ChemSpider
  • 4407
UNII
  • 695DKH33EI
ChEMBL
  • ChEMBL114655 checkY
CompTox Dashboard (EPA)
  • DTXSID4023387 Edit this at Wikidata
ECHA InfoCard100.006.531 Edit this at WikidataChemical and physical dataFormulaC19H25NO2Molar mass299.414 g·mol−13D model (JSmol)
  • Interactive image
  • OC(c1ccc(O)cc1)C(NC(C)CCc2ccccc2)C

Buphenine (or nylidrin; trade name Arlidin) is a β2 adrenoreceptor agonist[1] that acts as a vasodilator.[2]

It was developed as a chemical derivative of oxilofrine, and first reported in the literature in 1950.[3]

See also

  • Isoxsuprine

References

  1. ^ Mittag TW, Tormay A, Messenger M, Podos SM (February 1985). "Ocular hypotension in the rabbit. Receptor mechanisms of pirbuterol and nylidrin". Invest Ophthalmol Vis Sci. 26 (2): 163–9. PMID 2857689. Archived from the original on 2013-04-15.
  2. ^ Freedman L (1955). "Arlidin: a new vasodilative sympathomimetic drug". Angiology. 6 (1): 52–8. doi:10.1177/000331975500600106. PMID 14350296. S2CID 46317963.
  3. ^ Külz F, Schneider M (1950). "Über neue gefäßerweiternde Sympathomimetika" [On new vasodilative sympathomimetics]. Klin Wochenschr (in German). 28 (31–32): 535–7. doi:10.1007/BF01481535. PMID 14775050.
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Tocolytics/labor repressants (G02CA)
β2 adrenoreceptor agonists
Oxytocin antagonistsNSAIDsCalcium channel blockersMyosin inhibitors
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α1
Agonists
Antagonists
α2
Agonists
Antagonists
β
Agonists
Antagonists
  • See also: Receptor/signaling modulators
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AMPARTooltip α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor
KARTooltip Kainate receptor
NMDARTooltip N-Methyl-D-aspartate receptor
  • See also: Receptor/signaling modulators
  • Metabotropic glutamate receptor modulators
  • Glutamate metabolism/transport modulators


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