DPI-221
Chemical compound
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Formula | C31H38FN3O |
Molar mass | 487.651 |
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DPI-221 is an opioid drug that is used in scientific research. It is a highly selective agonist for the δ-opioid receptor, which produces fewer convulsions than most drugs from this family.[1]
References
- ^ Holt JD, Watson MJ, Chang JP, O'Neill SJ, Wei K, Pendergast W, et al. (November 2005). "DPI-221 [4-((alpha-s)-alpha-((2s,5r)-2,5-dimethyl-4-(3-fluorobenzyl)-1-piperazinyl)benzyl)-N,N-diethylbenzamide]: a novel nonpeptide delta receptor agonist producing increased micturition interval in normal rats". The Journal of Pharmacology and Experimental Therapeutics. 315 (2): 601–8. doi:10.1124/jpet.105.090498. PMID 16020629. S2CID 97486165.
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Opioid receptor modulators
(MOR)
(DOR)
(KOR)
(NOP)
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Antagonists |
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- Enkephalinase inhibitors: Amastatin
- BL-2401
- Candoxatril
- D -Phenylalanine
- Dexecadotril (retorphan)
- Ecadotril (sinorphan)
- Kelatorphan
- Racecadotril (acetorphan)
- RB-101
- RB-120
- RB-3007
- Opiorphan
- Selank
- Semax
- Spinorphin
- Thiorphan
- Tynorphin
- Ubenimex (bestatin)
- Propeptides: β-Lipotropin (proendorphin)
- Prodynorphin
- Proenkephalin
- Pronociceptin
- Proopiomelanocortin (POMC)
- Others: Kyotorphin (met-enkephalin releaser/degradation stabilizer)
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