Impromidine

Chemical compound
  • none
Identifiers
  • 2-[3-(1H-imidazol-5-yl)propyl]-1-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine
CAS Number
  • 55273-05-7 checkY
PubChem CID
  • 41376
IUPHAR/BPS
  • 1226
ChemSpider
  • 37757 ☒N
UNII
  • 931L4X5WMM
ChEMBL
  • ChEMBL12608 ☒N
CompTox Dashboard (EPA)
  • DTXSID90203780 Edit this at Wikidata
Chemical and physical dataFormulaC14H23N7SMolar mass321.45 g·mol−13D model (JSmol)
  • Interactive image
  • Cc1[nH]cnc1CSCCNC(=N)NCCCc2c[nH]cn2
InChI
  • InChI=1S/C14H23N7S/c1-11-13(21-10-19-11)8-22-6-5-18-14(15)17-4-2-3-12-7-16-9-20-12/h7,9-10H,2-6,8H2,1H3,(H,16,20)(H,19,21)(H3,15,17,18) ☒N
  • Key:MURRAGMMNAYLNA-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Impromidine (INN) is a highly potent and specific histamine H2 receptor agonist.[1]

It has been used diagnostically as a gastric secretion indicator.

See also

  • Histamine agonists

References

  1. ^ Durant G, Duncan W, Ganellin C, Parsons M, Blakemore R, Rasmussen A (1978). "Impromidine (SK&F 92676) is a very potent and specific agonist for histamine H2 receptors". Nature. 276 (5686): 403–5. doi:10.1038/276403a0. PMID 714166. S2CID 4242863.
  • v
  • t
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Histamine receptor modulators
H1
Agonists
Antagonists
  • Unknown/unsorted: Azanator
  • Belarizine
  • Elbanizine
  • Flotrenizine
  • GSK1004723
  • Napactadine
  • Tagorizine
  • Trelnarizine
  • Trenizine
H2
Agonists
Antagonists
H3
Agonists
Antagonists
H4
Agonists
Antagonists
See also
Receptor/signaling modulators
Monoamine metabolism modulators
Monoamine reuptake inhibitors


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